Fig. 1 · Structure
Documents & Downloads
Fmoc-11-aminoundecanoic acid
PROTAC Linker
Fmoc-11-aminoundecanoic acid functions as a versatile PROTAC linker in the development of PROTACs and various conjugation strategies. This compound features an elongated alkane chain, with a terminal Fmoc-protected amine and a carboxylic acid group, providing essential functional capabilities for research applications. The Fmoc group can be selectively removed under basic conditions to yield a free amine, suitable for subsequent conjugations. Additionally, its terminal carboxylic acid is reactive towards primary amines in the presence of coupling agents like EDC or HATU, facilitating the formation of stable amide bonds for diverse biochemical investigations.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 88574-07-6 |
| Applications | PROTAC Linker |
| Formula | C26H33NO4 |
| Molecular Weight | 423.54 |
| SMILES | O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)NCCCCCCCCCCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.