Fmoc-11-aminoundecanoic acid functions as a versatile PROTAC linker in the development of PROTACs and various conjugation strategies. This compound features an elongated alkane chain, with a terminal Fmoc-protected amine and a carboxylic acid group, providing essential functional capabilities for research applications. The Fmoc group can be selectively removed under basic conditions to yield a free amine, suitable for subsequent conjugations. Additionally, its terminal carboxylic acid is reactive towards primary amines in the presence of coupling agents like EDC or HATU, facilitating the formation of stable amide bonds for diverse biochemical investigations.
Fmoc-11-aminoundecanoic acid functions as a versatile PROTAC linker in the development of PROTACs and various conjugation strategies. This compound features an elongated alkane chain, with a terminal Fmoc-protected amine and a carboxylic acid group, providing essential functional capabilities for research applications. The Fmoc group can be selectively removed under basic conditions to yield a free amine, suitable for subsequent conjugations. Additionally, its terminal carboxylic acid is reactive towards primary amines in the presence of coupling agents like EDC or HATU, facilitating the formation of stable amide bonds for diverse biochemical investigations.
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