Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH

Catalog No.: A43278
ADC Linker
Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH functions as a cleavable linker for antibody-drug conjugates (ADCs). This compound enables the selective release of cytotoxic drugs upon internalization by target cells, enhancing the efficacy and specificity of cancer therapies. It is widely used in the development of ADCs for various research applications, including targeted delivery and controlled drug release studies.
Grouped product items
Size Price Stock Qty
25mg
$4,200.00
In stock
50mg
$6,535.00
In stock
100mg
$10,160.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFmoc-Ala-Ala-Ala-amide-C-O-C-COOH functions as a cleavable linker for antibody-drug conjugates (ADCs). This compound enables the selective release of cytotoxic drugs upon internalization by target cells, enhancing the efficacy and specificity of cancer therapies. It is widely used in the development of ADCs for various research applications, including targeted delivery and controlled drug release studies.
Product Information
Catalog NumA43278
FormulaC27H32N4O8
Molecular Weight540.56
CAS Number3002986-41-3
SMILESOC(COCNC([C@H](C)NC([C@H](C)NC([C@H](C)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=O)=O)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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