Fmoc-Ala-Ala-OH is a self-assembling dipeptide featuring a fluorenylmethoxycarbonyl (Fmoc) moiety, designed for creating nanofiber networks. When exposed to conditions below pH 4, this dipeptide forms a hydrogel scaffold with over 99% water content, exhibiting fiber diameters around 22 nm that closely resemble extracellular matrix (ECM) components. Fmoc-Ala-Ala-OH facilitates cell adhesion and proliferation while preserving cellular phenotype, thereby mimicking the ECM. This reagent is particularly valuable in tissue engineering and 3D cell culture applications, making it ideal for in vitro studies of chondrocytes and other cell types.
Fmoc-Ala-Ala-OH is a self-assembling dipeptide featuring a fluorenylmethoxycarbonyl (Fmoc) moiety, designed for creating nanofiber networks. When exposed to conditions below pH 4, this dipeptide forms a hydrogel scaffold with over 99% water content, exhibiting fiber diameters around 22 nm that closely resemble extracellular matrix (ECM) components. Fmoc-Ala-Ala-OH facilitates cell adhesion and proliferation while preserving cellular phenotype, thereby mimicking the ECM. This reagent is particularly valuable in tissue engineering and 3D cell culture applications, making it ideal for in vitro studies of chondrocytes and other cell types.
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