Fig. 1 · Structure

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Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz

PROTAC Linker

Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz is a versatile PROTAC linker designed for targeted protein degradation applications. This compound facilitates the assembly of PROTAC molecules, enabling the selective degradation of target proteins. It is particularly useful in synthesizing complex structures, including those related to Deruxtecan research, thus contributing to studies in cancer therapy and biochemistry.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2264011-97-2
Applications PROTAC Linker
Formula C40H41N5O9
Molecular Weight 735.78
SMILES
O=C(OCC1=CC=CC=C1)COCNC(CNC([C@H](CC2=CC=CC=C2)NC(CNC(CNC(OCC3C4=CC=CC=C4C5=CC=CC=C53)=O)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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