Fmoc-Hyp(Bom)-OH

Catalog No.: A42864
ADC Linker
Fmoc-Hyp(Bom)-OH is a non-cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This compound features a unique structure that promotes effective conjugation while maintaining stability in biological systems. Additionally, Fmoc-Hyp(Bom)-OH can serve as an alkyl chain-based linker for the development of proteolysis-targeting chimeras (PROTACs), facilitating targeted protein degradation studies. Its versatile applications make it an essential tool for researchers in the fields of drug development and chemical biology.
Grouped product items
Size Price Stock Qty
1g
$20.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFmoc-Hyp(Bom)-OH is a non-cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This compound features a unique structure that promotes effective conjugation while maintaining stability in biological systems. Additionally, Fmoc-Hyp(Bom)-OH can serve as an alkyl chain-based linker for the development of proteolysis-targeting chimeras (PROTACs), facilitating targeted protein degradation studies. Its versatile applications make it an essential tool for researchers in the fields of drug development and chemical biology.
Product Information
Catalog NumA42864
FormulaC28H33N3O8
Molecular Weight539.58
CAS Number187223-15-0
SMILESO=C(O)[C@@H]1C[C@@H](OC(NCCNC(OC(C)(C)C)=O)=O)CN1C(OCC2C3=C(C=CC=C3)C4=C2C=CC=C4)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2