Fig. 1 · Structure
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Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester)
BFC
Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester) is a bifunctional chelator (BFC) that serves as a macrocyclic DOTA derivative, primarily utilized for tumor pre-targeting applications. This reagent facilitates the conjugation of peptides and radionuclides, enhancing the specificity and efficacy of imaging and therapeutic strategies in cancer research. Its unique structural properties make it a valuable tool for developing targeted radiopharmaceuticals.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 479081-06-6 |
| Applications | BFC |
| Formula | C49H74N6O11 |
| Molecular Weight | 923.15 |
| SMILES | CC(C)(C)OC(CN(CCN(CCN(CC1)CC(OC(C)(C)C)=O)CC(OC(C)(C)C)=O)CCN1CC(NCCCC[C@@H](C(O)=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.