Fmoc-Lys(Pal-Glu-OtBu)-OH is a non-cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs). This compound features a lysine residue with a palmitic acid-modified glutamic acid and tert-butyl ester, providing enhanced stability and solubility. Its structure also allows for use as an alkyl chain-based linker in the development of proteolysis-targeting chimeras (PROTACs), facilitating targeted protein degradation in various research applications. This versatility makes it a valuable reagent for advanced bioconjugation techniques and drug delivery systems.
Fmoc-Lys(Pal-Glu-OtBu)-OH is a non-cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs). This compound features a lysine residue with a palmitic acid-modified glutamic acid and tert-butyl ester, providing enhanced stability and solubility. Its structure also allows for use as an alkyl chain-based linker in the development of proteolysis-targeting chimeras (PROTACs), facilitating targeted protein degradation in various research applications. This versatility makes it a valuable reagent for advanced bioconjugation techniques and drug delivery systems.
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