Fmoc-N-methyl-PEG3-CH2CH2COOH

Catalog No.: A43076
ADC Linker
Fmoc-N-methyl-PEG3-CH2CH2COOH is a PEG-based cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound facilitates the effective transport of drug payloads to target cells, enhancing therapeutic efficacy while minimizing off-target effects. Additionally, it serves as a versatile linker in the development of PROTACs (proteolysis-targeting chimeras), supporting research in targeted protein degradation and drug discovery applications.
Grouped product items
Size Price Stock Qty
50mg
$165.00
In stock
100mg
$255.00
In stock
250mg
$450.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFmoc-N-methyl-PEG3-CH2CH2COOH is a PEG-based cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound facilitates the effective transport of drug payloads to target cells, enhancing therapeutic efficacy while minimizing off-target effects. Additionally, it serves as a versatile linker in the development of PROTACs (proteolysis-targeting chimeras), supporting research in targeted protein degradation and drug discovery applications.
Product Information
Catalog NumA43076
FormulaC25H31NO7
Molecular Weight457.52
CAS Number1807518-77-9
SMILESO=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)N(C)CCOCCOCCOCCC(O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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