Fig. 1 · Structure
Documents & Downloads
Fmoc-N-PEG24-acid
PROTAC Linkers
Fmoc-N-PEG24-acid is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of protein-targeting warheads to E3 ligase recruiters, enabling targeted protein degradation. Its hydrophilic properties contribute to enhanced solubility and bioavailability, making it suitable for various biochemical and cellular studies related to protein control mechanisms in research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2170484-59-8 |
| Applications | PROTAC Linkers |
| Formula | C66H113NO28 |
| Molecular Weight | 1368.59 |
| SMILES | O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)OCC1C(C=CC=C2)=C2C3=C1C=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.