Fig. 1 · Structure

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Fmoc-NH-PEG3-amide-CH2OCH2COOH

PROTAC Linker

Fmoc-NH-PEG3-amide-CH2OCH2COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the solubility and biocompatibility of PROTACs, facilitating efficient target degradation in cellular assays. It is suitable for research applications focusing on protein modulation and the development of novel therapeutic agents.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 489427-26-1
Applications PROTAC Linker
Formula C27H34N2O9
Molecular Weight 530.57
SMILES
O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCNC(COCC(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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