Fig. 1 · Structure

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Fmoc-PEG5-NHS ester

PROTAC Linker

Fmoc-PEG5-NHS ester is a polyethylene glycol (PEG) linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the conjugation of target proteins with E3 ligases, thereby promoting targeted protein degradation. Fmoc-PEG5-NHS ester is particularly valuable in research applications involving selective modulation of protein levels and the study of cellular pathways.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1402080-11-8
Applications PROTAC Linker
Formula C32H40N2O11
Molecular Weight 628.67
SMILES
O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCOCCOCCC(ON4C(CCC4=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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