Fig. 1 · Structure
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Fomivirsen sodium
CMV Inhibitor
Fomivirsen sodium is an antisense 21-mer phosphorothioate oligonucleotide that selectively targets the cytomegalovirus (CMV) immediate-early 2 protein mRNAs. This antiviral agent is primarily utilized in research related to CMV retinitis, particularly in the context of AIDS-related studies. By binding to and facilitating the degradation of CMV mRNAs, Fomivirsen sodium effectively inhibits viral proliferation, making it a valuable tool for investigating CMV pathogenesis and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 160369-77-7 |
| Applications | CMV Inhibitor |
| Molecular Weight | 6682.4 (free acid) |
| Synonyms | ISIS-2922 sodium |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.