Fig. 1 · Structure
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Fosifloxuridine nafalbenamide
Thymidylate Synthase Inhibitor
Fosifloxuridine nafalbenamide is a thymidylate synthase inhibitor, functioning as a pyrimidine nucleotide analogue. This compound exhibits significant anticancer activity by disrupting nucleotide synthesis essential for DNA replication. Additionally, Fosifloxuridine nafalbenamide has potential applications in eliciting host immune responses, making it a valuable tool for research in immunology and cancer therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1332837-31-6 |
| Applications | Thymidylate Synthase Inhibitor |
| Formula | C29H29FN3O9P |
| Molecular Weight | 613.53 |
| Synonyms | NUC-3373 |
| SMILES | O=P(OC[C@H]1O[C@@H](N(C=C(F)C2=O)C(N2)=O)C[C@@H]1O)(N[C@@H](C)C(OCC3=CC=CC=C3)=O)OC4=CC=CC5=C4C=CC=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.