Fig. 1 · Structure

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Fosrolapitant

Neurokinin 1 Receptor Antagonist

Fosrolapitant is a selective neurokinin 1 (NK1) receptor antagonist, primarily utilized in the study of pain and anxiety pathways. By inhibiting NK1 receptor activity, it effectively alleviates symptoms related to various neurogenic processes. This compound is valuable for research applications involving the modulation of neurokinin signaling in both preclinical and clinical settings.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 2573694-38-7
Applications Neurokinin 1 Receptor Antagonist
Formula C27H29F6N2O8P
Molecular Weight 654.49
SMILES
C[C@H](C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)OC[C@]2(C3=CC=CC=C3)N(C[C@]4(NC(CC4)=O)CC2)C(OCOP(O)(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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