Fig. 1 · Structure
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Fostriecin sodium
Protein Phosphatase Inhibitor
Fostriecin sodium is an antibiotic that serves as a potent inhibitor of protein phosphatases, specifically PP2 and PP4, with IC50 values of 1.5 nM and 3 nM, respectively. This compound exhibits cytotoxic properties, making it a valuable tool for studying the role of protein phosphorylation in cell signaling and cancer research. Its selective protein phosphatase inhibition supports investigations into therapeutic strategies targeting phosphatase-related pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 87860-39-7 |
| Applications | Protein Phosphatase Inhibitor |
| Formula | C19H26NaO9P |
| Molecular Weight | 452.37 |
| Synonyms | PD 110161 sodium; CL 1565A sodium; CI-920 sodium |
| SMILES | O=C(C=CC1)O[C@H]1/C=C/[C@@](C)(O)[C@H](OP(O)(O[Na])=O)C[C@@H](O)/C=C\C=C/C=C/CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.