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FR 113680

Substance P Antagonist

FR 113680 is a tripeptide antagonist that selectively targets the NK1 neurokinin receptor, inhibiting the action of substance P. This compound displays significant biological activity in modulating pain and inflammatory responses. It is widely utilized in research exploring the role of neurokinin pathways in various neurological and psychiatric disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	126088-92-4
Applications	Substance P Antagonist
Formula	C₃₅H₃₉N₅O₆
Molecular Weight	625.71
SMILES	C[C@@H](O)[C@H](NC(C)=O)C(=O)N[C@H](Cc1cn(C=O)c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N(C)Cc1ccccc1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.