FR-181877

Name: FR-181877
Brand: Adooq Bioscience
SKU: A63326
Rating: 5 (288 reviews)

Catalog No.: A63326

PGI2 Agonist

FR-181877 is a selective PGI2 agonist that enhances prostacyclin signaling. It exhibits significant inhibitory activity on ADP-induced human platelet aggregation, with an IC50 value of 0.081 μM. This compound is valuable for research focusing on cardiovascular biology and hemostasis, offering insights into platelet function and potential therapeutic applications in thrombotic disorders.

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Grouped product items
Size	Price	Stock
25mg	$1,655.00	In stock
50mg	$2,115.00	In stock
100mg	$2,720.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	FR-181877 is a selective PGI2 agonist that enhances prostacyclin signaling. It exhibits significant inhibitory activity on ADP-induced human platelet aggregation, with an IC50 value of 0.081 μM. This compound is valuable for research focusing on cardiovascular biology and hemostasis, offering insights into platelet function and potential therapeutic applications in thrombotic disorders.

Product Information

Catalog Num	A63326
Formula	C30H28N2O4
Molecular Weight	480.55
CAS Number	172936-99-1
SMILES	OC(COC1=C(CC2)C(C[C@H]2CN(C(C=C3)=O)N=C3C(C4=CC=CC=C4)C5=CC=CC=C5)=CC=C1)=O

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