Fig. 1 · Structure

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FR168888

Na+/H+ Exchange Inhibitor

FR168888 is a potent inhibitor of Na+/H+ exchange, exhibiting a Ki value of 6.4 nM. This compound effectively disrupts the Na+/H+ exchange process, making it a valuable tool for studying cellular pH regulation and ion homeostasis. FR168888 is applicable in research exploring the mechanisms of hypertension, heart failure, and other cardiovascular diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 168620-46-0
Applications Na+/H+ Exchange Inhibitor
Formula C14H18N4O5S
Molecular Weight 354.38
SMILES
O=C(NC(N)=N)C1=CC(N2C=CC=C2)=CC(CO)=C1.CS(=O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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