Fig. 1 · Structure
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FR181157
PGI2 Agonist
FR181157 is an orally active prostacyclin (PGI2) agonist that exhibits favorable pharmacokinetic properties. It plays a crucial role in promoting vasodilation and inhibiting platelet aggregation, making it valuable for research in cardiovascular disorders and pulmonary hypertension. Its potent biological activity provides a useful tool for understanding the therapeutic potential of PGI2 modulation in various disease models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 171046-15-4 |
| Applications | PGI2 Agonist |
| Formula | C30H26NNaO4 |
| Molecular Weight | 487.52 |
| SMILES | O=C(O[Na])COC1=CC=CC(C[C@H]2C(C3=NC(C4=CC=CC=C4)=C(C5=CC=CC=C5)O3)=CCCC2)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.