Fig. 1 · Structure
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FR900098 sodium
Antimalarial Agent
FR900098 sodium is an antimalarial agent that selectively inhibits 1-deoxy-D-xylulose-5-phosphate (DXP) reductoisomerase, an enzyme crucial for isoprenoid biosynthesis in Plasmodium species. This compound demonstrates notable biological activity against malaria parasites while exhibiting no significant acute toxicity or genotoxic effects. Additionally, FR900098 sodium does not induce chromosome breakage or affect bone marrow red blood cells in NMRI mice, making it a valuable tool for malaria research and potential therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 73226-73-0 |
| Applications | Antimalarial Agent |
| Formula | C5H11NNaO5P |
| Molecular Weight | 219.11 |
| SMILES | O=C(C)N(CCCP(O)(O[Na])=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.