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Biological Activity
Fulvestrant R enantiomer (ICI 182780 R enantiomer; ZD 9238 R enantiomer; ZM 182780 R enantiomer) is the less active R enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.48 mL | 82.4 mL | 164.81 mL |
| 0.5 mM | 3.3 mL | 16.48 mL | 32.96 mL |
| 1 mM | 1.65 mL | 8.24 mL | 16.48 mL |
| 5 mM | 0.33 mL | 1.65 mL | 3.3 mL |
*The above data is based on the productmolecular weight 606.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21545 |
|---|---|
| Actions | Antagonist |
| CAS No. | 1807900-80-6 |
| Formula | C32H47F5O3S |
| M. Wt | 606.77 |
| Purity | >98% |
| Synonyms | ICI 182780 R enantiomer, ICI182780, ICI-182780; ZD 9238 R enantiomer, ZD9238, ZD-9238; ZM 182780 R enantiomer |
| SMILES | C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])[C@H](CCCCCCCCC[S@](CCCC(F)(F)C(F)(F)F)=O)CC4=C(C=CC(O)=C4)[C@@]3([H])CC2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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