Furathiocarb is a carbamate pro-insecticide that primarily targets insect nervous systems. It exhibits significant biological activity by inducing the proliferation of MHC II-positive B cells in auricular lymph nodes and promoting the production of Th1 cytokines, including IL-2, TNF-γ, and IFN-γ. Furathiocarb has applications in contact allergy research, demonstrating no respiratory allergy induction in mice. After dermal absorption in isolated rats, it is fully metabolized to carbofuran, with skin permeation rates for emulsifiable concentrate and wettable powder formulations exceeding those of the parent compound.
Furathiocarb is a carbamate pro-insecticide that primarily targets insect nervous systems. It exhibits significant biological activity by inducing the proliferation of MHC II-positive B cells in auricular lymph nodes and promoting the production of Th1 cytokines, including IL-2, TNF-γ, and IFN-γ. Furathiocarb has applications in contact allergy research, demonstrating no respiratory allergy induction in mice. After dermal absorption in isolated rats, it is fully metabolized to carbofuran, with skin permeation rates for emulsifiable concentrate and wettable powder formulations exceeding those of the parent compound.
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