FXR/TGR5 agonist 1

Catalog No.: A60400
GPBAR1 Agonist
FXR/TGR5 agonist 1 is a potent agonist of the G protein-coupled receptor TGR5 (GPBAR1) and also activates farnesoid X receptor (FXR). This compound demonstrates key biological activity in regulating metabolic pathways associated with lipid metabolism and inflammation. It is primarily utilized in research applications focusing on fatty liver disease and related metabolic disorders.
Grouped product items
Size Price Stock Qty
1mg
$750.00
In stock
5mg
$1,925.00
In stock
10mg
$2,960.00
In stock
25mg
$8,460.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionFXR/TGR5 agonist 1 is a potent agonist of the G protein-coupled receptor TGR5 (GPBAR1) and also activates farnesoid X receptor (FXR). This compound demonstrates key biological activity in regulating metabolic pathways associated with lipid metabolism and inflammation. It is primarily utilized in research applications focusing on fatty liver disease and related metabolic disorders.
Product Information
Catalog NumA60400
FormulaC31H32ClN3O3
Molecular Weight530.06
CAS Number2677689-72-2
SMILESO=C(C1=C(C)C=NC=C1)N(C2=CC(OC)=CC(Cl)=C2)CC3(CC4)CCC4(C5=CC=C(OC)C(C#N)=C5)CC3
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