G(IIKK)3I-NH2

Catalog No.: A49306
Antimicrobial Peptide
G(IIKK)3I-NH2 is an antimicrobial peptide that targets bacterial membranes, exhibiting significant antibacterial properties against both Gram-negative and Gram-positive bacteria. This peptide demonstrates low toxicity in primary cells and mouse models, making it a suitable candidate for therapeutic applications. Additionally, G(IIKK)3I-NH2 is noted for its ability to resist induction of bacterial resistance, positioning it as a valuable reagent in the research of anti-infection agents.
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionG(IIKK)3I-NH2 is an antimicrobial peptide that targets bacterial membranes, exhibiting significant antibacterial properties against both Gram-negative and Gram-positive bacteria. This peptide demonstrates low toxicity in primary cells and mouse models, making it a suitable candidate for therapeutic applications. Additionally, G(IIKK)3I-NH2 is noted for its ability to resist induction of bacterial resistance, positioning it as a valuable reagent in the research of anti-infection agents.
Product Information
Catalog NumA49306
FormulaC80H155N21O14
Molecular Weight1635.22
CAS Number1338598-65-4
SequenceGly-Ile-Ile-Lys-Lys-Ile-Ile-Lys-Lys-Ile-Ile-Lys-Lys-Ile-NH2
Sequence shorteningGIIKKIIKKIIKKI-NH2
SMILES[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(N)=O)=O)CCCCN)=O)CCCCN)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCCCN)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCCCN)=O)CCCCN)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCCCN
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