Fig. 1 · Structure
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Galanthamine N-Oxide
AChE Inhibitor
Galanthamine N-Oxide is an acetylcholinesterase (AChE) inhibitor derived from the bulbs of Zephyranthes concolor. It exhibits a potent inhibitory effect on electric eel AChE with an EC50 value of 26.2 μM. Additionally, Galanthamine N-Oxide effectively hampers substrate accommodation in the active sites of Torpedo californica AChE, human AChE, and human butyrylcholinesterase (hBChE), making it a valuable tool for research in neuropharmacology and cholinergic signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 134332-50-6 |
| Applications | AChE Inhibitor |
| Formula | C17H21NO4 |
| Molecular Weight | 303.35 |
| SMILES | O[C@H]1C=C[C@@]23CC[N@@+](C)([O-])CC4=CC=C(OC)C(O[C@@]3([H])C1)=C24 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.