Fig. 1 · Structure
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(-)-Gallopamil hydrochloride ((-)-Methoxyverapamil hydrochloride)
Fast Voltage-Dependent Inactivation Modulator
(-)-Gallopamil hydrochloride is a selective modulator of fast voltage-dependent inactivation, specifically targeting Cav1.2 channels formed by β-subunits. This compound effectively inhibits these channels, leading to an acceleration of both the voltage-dependent phase of ICa decay and the decay of Ba2+ currents. Its unique mechanism makes (-)-Gallopamil hydrochloride a valuable reagent for research in antiarrhythmic therapies and cardiovascular pharmacology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 36622-39-6 |
| Applications | Fast Voltage-Dependent Inactivation Modulator |
| Formula | C28H41ClN2O5 |
| Molecular Weight | 521.09 |
| Synonyms | (-)-Methoxyverapamil hydrochloride |
| SMILES | N#C[C@](C(C)C)(CCCN(CCC1=CC=C(OC)C(OC)=C1)C)C2=CC(OC)=C(OC)C(OC)=C2.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.