Fig. 1 · Structure
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(-)-Gallopamil ((-)-Methoxyverapamil)
Fast Voltage-Dependent Inactivation Modulator
(-)-Gallopamil acts as a selective modulator of fast voltage-dependent inactivation, targeting Cav1.2 constructs associated with β-subunits. This compound efficiently inhibits these constructs, promoting rapid inactivation and thereby accelerating the voltage-dependent phase of ICa decay, as well as the decay of Ba2+ currents. (-)-Gallopamil is a valuable reagent for research applications focused on antiarrhythmic drug development and cardiac electrophysiology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 36622-40-9 |
| Applications | Fast Voltage-Dependent Inactivation Modulator |
| Formula | C28H40N2O5 |
| Molecular Weight | 484.63 |
| Synonyms | (-)-Methoxyverapamil |
| SMILES | N#C[C@](CCCN(C)CCC1=CC=C(C(OC)=C1)OC)(C2=CC(OC)=C(C(OC)=C2)OC)C(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.