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GalNAc-L96 free base

Nucleic Acid Drugs Delivery

GalNAc-L96 free base is a triantennary GalNAc ligand designed to facilitate the delivery of nucleic acid drugs, particularly GalNAc-conjugated siRNA. By targeting the asialoglycoprotein receptor (ASGPR), GalNAc enhances cellular uptake and improves the therapeutic efficacy of RNA-based therapeutics. This compound is valuable for researchers focusing on gene silencing and RNA interference applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	1159408-61-3
Applications	Nucleic Acid Drugs Delivery
Formula	C₁₂₁H₁₇₉N₁₁O₄₅
Molecular Weight	2507.76
SMILES	CC(N[C@H]([C@H]([C@H]([C@H](O1)COC(C)=O)OC(C)=O)OC(C)=O)[C@@H]1OCCCCC(NCCCNC(CCOCC(COCCC(NCCCNC(CCCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)COC(C)=O)OC(C)=O)OC(C)=O)NC(C)=O)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)COC(C)=O)OC(C)=O)OC(C)=O)NC(C)=O)=O)=O)NC(CCCCCCCCCCC(N(C[C@@H](C4)OC(CCC(O)=O)=O)[C@@H]4COC(C5=CC=C(C=C5)OC)(C6=CC=CC=C6)C7=CC=C(C=C7)OC)=O)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.