Fig. 1 · Structure
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GalNAc-L96
Nucleic Acid Drugs Delivery
GalNAc-L96 is a triantennary N-acetylgalactosamine (GalNAc) that functions as a ligand for the asialoglycoprotein receptor (ASGPR). This compound is primarily utilized for the synthesis of GalNAc-siRNA, facilitating targeted delivery of nucleic acid drugs. Its efficacy in enhancing oligonucleotide delivery makes it a valuable tool for research applications focused on gene silencing and RNA-based therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 1159408-62-4 |
| Applications | Nucleic Acid Drugs Delivery |
| Formula | C127H194N12O45 |
| Molecular Weight | 2608.95 |
| SMILES | O=C(CCCCCCCCCCC(N1[C@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)C[C@@H](OC(CCC(O)=O)=O)C1)=O)NC(COCCC(NCCCNC(CCCCO[C@H]5[C@H](NC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)O5)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]6[C@H](NC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)O6)=O)=O)COCCC(NCCCNC(CCCCO[C@H]7[C@H](NC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)O7)=O)=O.CCN(CC)CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.