Fig. 1 · Structure
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gamma-DGG TFA
EPSP Antagonist
gamma-DGG TFA is a potent EPSP antagonist that effectively disrupts excitatory amino acid signaling. This compound inhibits depolarization induced by NMDA, Kainate, and Quisqualate in rat hippocampal slices, providing valuable insights into synaptic transmission and neuronal excitability. Its utility in studying excitatory neurotransmission makes it an essential tool for researchers investigating mechanisms of synaptic plasticity and related neurological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 71822-19-0 |
| Applications | EPSP Antagonist |
| Formula | C9H13F3N2O7 |
| Molecular Weight | 318.20 |
| Synonyms | γDGG TFA; γ-D-Glutamylglycine TFA |
| SMILES | OC(C(F)(F)F)=O.OC(CNC(CC[C@@H](N)C(O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.