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Ganglioside GM1 ammonium

Ganglioside

Ganglioside GM1 ammonium is a monosialylated ganglioside that serves as a key component in cellular membranes, particularly in the brain. It provides neuroprotection by exhibiting anti-inflammatory properties and modulating membrane fluidity, which enhances the retention of gangliosides in lipid rafts. Ganglioside GM1 ammonium plays a critical role in neuronal differentiation and potentiates responses to neurotrophic factors, while also protecting neurons from excitotoxic damage. This compound is relevant in the study of neurodegenerative diseases, including Alzheimer’s disease, and offers insight into therapeutic strategies for neuroprotection and cell survival.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1329115-44-7
Applications	Ganglioside
Formula	C₇₃H₁₃₄N₄O₃₁
Molecular Weight	1563.85
Synonyms	GM1 (d18:1/C18:0) ammonium; C18 Ganglioside GM1 (d18:1/18:0) ammonium
SMILES	OC([C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)O[C@H]([C@H]([C@@H](O[C@@H]2CO)O[C@@H]3[C@H](O[C@H]([C@@H]([C@H]3O)O)OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCCCC)=O)CO)O)[C@H]2O[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O[C@@H]5O[C@@H]([C@@H]([C@@H]([C@H]5O)O)O)CO)NC(C)=O)=O.N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.