Fig. 1 · Structure

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Ganglioside GM2, Asialo

Biochemical Assay Reagent

Ganglioside GM2, Asialo is a glycosphingolipid that lacks a sialic acid residue, distinguishing it from ganglioside M2. It primarily serves as a biochemical assay reagent and is relevant in the study of neurodegenerative diseases such as Tay-Sachs and Sandhoff disease, which are characterized by lysosomal hexosaminidase A and B deficiencies. Asialo-GM2 is also known to interact with various bacteria, notably Pseudomonas, which can be isolated from cystic fibrosis patients. This product consists of a mixture of asialo-GM2 molecular species featuring fatty acyl chains of variable length, facilitating diverse research applications.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 35960-33-9
Applications Biochemical Assay Reagent
Formula C56H104N2O18
Molecular Weight 1093.43
Synonyms Gangliotriosylceramide
SMILES
CCCCCCCCCCCCCCCCCC(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)CO[C@H]1C(O)C(O)[C@H](O[C@H]2C(O)[C@@H](O)[C@@H](O[C@@H]3C(NC(C)=O)C(O)[C@@H](O)[C@@H](O3)CO)C(O2)CO)[C@@H](O1)CO)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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