Fig. 1 · Structure
Documents & Downloads
Ganstigmine hydrochloride
AChE Inhibitor
Ganstigmine hydrochloride is an orally active inhibitor of acetylcholinesterase (AChE) that enhances the release of soluble amyloid precursor protein alpha (sAPPα) from neuroblastoma cells. This compound has been shown to increase acetylcholine levels in the prefrontal cortex of rats, making it a valuable tool in the study of cholinergic signaling. Ganstigmine hydrochloride is primarily utilized in research focused on neurological disorders, particularly Alzheimer's disease, to explore its implications in cognitive function and neuroprotection.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 412044-92-9 |
| Applications | AChE Inhibitor |
| Formula | C21H26ClN3O3 |
| Molecular Weight | 403.90 |
| Synonyms | CHF 2819 |
| SMILES | O=C(OC1=CC2=C(N[C@]3([H])[C@@]2(C)CC[N@+]3([O-])C)C=C1)NC4=CC=CC=C4CC.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.