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Garcinol is a polyisoprenylated benzophenone derivative isolated from Garcinia indica. It is a potent inhibitor of histone acetyltransferases (HATs) p300 (IC50=7µM) and PCAF (IC50=5µM) both in vitro and in vivo.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.59 mL | 82.95 mL | 165.89 mL |
| 0.5 mM | 3.32 mL | 16.59 mL | 33.18 mL |
| 1 mM | 1.66 mL | 8.29 mL | 16.59 mL |
| 5 mM | 0.33 mL | 1.66 mL | 3.32 mL |
*The above data is based on the productmolecular weight 602.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12814 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 78824-30-3 |
| Formula | C38H50O6 |
| M. Wt | 602.8 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | camboginol |
| SMILES | CC(=CC[[email protected]@H]1C[[email protected]@]2(C(=O)/C(=C(\C3=CC(=C(C=C3)O)O)/O)/C(=O)[[email protected]@](C2=O)(C1(C)C)CC=C(C)C)C[[email protected]](CC=C(C)C)C(=C)C)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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