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Garcinone B

Mpro Inhibitor

Garcinone B is a xanthone derivative that functions as a potent inhibitor of the main protease (Mpro) and angiotensin-converting enzyme 2 (ACE2). Isolated from the pericarp of Mangosteen, Garcinone B exhibits significant biological activity that may contribute to antiviral research, particularly in the context of COVID-19. This compound serves as a valuable tool for investigations into therapeutic strategies targeting viral replication and infection pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	76996-28-6
Applications	Mpro Inhibitor
Formula	C₂₃H₂₂O₆
Molecular Weight	394.42
SMILES	OC(C(C/C=C(C)/C)=C1O)=CC2=C1C(C3=C4C(OC(C)(C)C=C4)=C(O)C=C3O2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.