Gatuzosiran

Catalog No.: A69055
HSD17B13 synthesis reducer
Gatuzosiran is a small interfering RNA (siRNA) that targets and reduces the synthesis of 17-beta-hydroxysteroid dehydrogenase 13 (HSD17B13). This compound plays a crucial role in research focused on fatty liver disease, providing insights into the molecular mechanisms underlying lipid metabolism and liver function. Its ability to modulate HSD17B13 expression makes it a valuable tool for studying the pathophysiology of liver diseases.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGatuzosiran is a small interfering RNA (siRNA) that targets and reduces the synthesis of 17-beta-hydroxysteroid dehydrogenase 13 (HSD17B13). This compound plays a crucial role in research focused on fatty liver disease, providing insights into the molecular mechanisms underlying lipid metabolism and liver function. Its ability to modulate HSD17B13 expression makes it a valuable tool for studying the pathophysiology of liver diseases.
Product Information
Catalog NumA69055
FormulaC493H653F11N163O311P43S7
Molecular Weight15603.70
CAS Number2409783-34-0
SMILES[Gatuzosiran]
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