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GB110 is a Novel potent non-peptide PAR2 agonist. GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.43 mL | 82.13 mL | 164.26 mL |
| 0.5 mM | 3.29 mL | 16.43 mL | 32.85 mL |
| 1 mM | 1.64 mL | 8.21 mL | 16.43 mL |
| 5 mM | 0.33 mL | 1.64 mL | 3.29 mL |
*The above data is based on the productmolecular weight 608.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18755 |
|---|---|
| Actions | Agonist |
| CAS No. | 1252806-70-4 |
| Formula | C33H48N6O5 |
| M. Wt | 608.78 |
| Purity | >98% |
| Synonyms | GB110; GB-110; GB 110 |
| SMILES | O=C(C1=CC=NO1)N[[email protected]@H](CC2CCCCC2)C(N[[email protected]@H]([[email protected]@H](C)CC)C(NCC3=CC=CC(C(N4CCC(CN)CC4)=O)=C3)=O)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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