Fig. 1 · Structure

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GBR-12879 dihydrochloride

Dopamine Uptake Inhibitor

GBR-12879 dihydrochloride is a potent dopamine uptake inhibitor that selectively targets the dopamine transporter. Its primary mechanism involves preventing the reabsorption of dopamine, thus enhancing dopaminergic signaling. This compound is widely utilized in research to investigate the role of dopamine in neurological disorders and to explore potential therapeutic strategies for conditions such as depression and schizophrenia.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 67469-45-8
Applications Dopamine Uptake Inhibitor
Formula C28H32Cl2F2N2O
Molecular Weight 521.47
SMILES
FC1=CC=C(C(C2=CC=C(F)C=C2)OCCN3CCN(C/C=C/C4=CC=CC=C4)CC3)C=C1.Cl.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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