GDC-0623

Catalog No.: A12974

MEK1 inhibitor

GDC-0623

GDC-0623 Chemical Structure

CAS NO. 1168091-68-6

GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $140.00

Special Price $112.00

10 mg

Regular Price: $250.00

Special Price $200.00

25 mg

Regular Price: $550.00

Special Price $440.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.
Targets
MEK1
0.13 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.92 mL 109.6 mL 219.2 mL
0.5 mM 4.38 mL 21.92 mL 43.84 mL
1 mM 2.19 mL 10.96 mL 21.92 mL
5 mM 0.44 mL 2.19 mL 4.38 mL

*The above data is based on the productmolecular weight 456.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A12974
Actions Inhibitor
M. Wt 456.21
Formula C16H14FIN4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1168091-68-6
Synonyms GDC0623, GDC 0632
SMILES O=C(C1=C(NC2=CC=C(I)C=C2F)N3C(C=C1)=CN=C3)NOCCO

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