Geldanamycin

Catalog No.: A11025

Hsp90 inhibitor

Geldanamycin

Geldanamycin Chemical Structure

CAS NO. 30562-34-6

Geldanamycin binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $60.00

Special Price $48.00

10 mg

Regular Price: $100.00

Special Price $80.00

50 mg

Regular Price: $400.00

Special Price $320.00

100 mg

Regular Price: $600.00

Special Price $480.00

10mM * 1mL in DMSO
$126.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Geldanamycin binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity.
Targets
p185 HSP90 (N-terminal domain) HSP90
70 nM0.78 μM(Kd)1.2 μM(Kd)
In vitro DMSO 100 mg/mL heating (178.36 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.84 mL 89.19 mL 178.38 mL
0.5 mM 3.57 mL 17.84 mL 35.68 mL
1 mM 1.78 mL 8.92 mL 17.84 mL
5 mM 0.36 mL 1.78 mL 3.57 mL

*The above data is based on the productmolecular weight 560.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A11025
Actions Inhibitor
M. Wt 560.6
Formula C29H40N2O9
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 30562-34-6
Synonyms N/A
SMILES C[[email protected]]1C[[email protected]@H]([[email protected]@H]([[email protected]](/C=C(/[[email protected]@H]([[email protected]](/C=C/C=C(/C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)\C)OC)OC(=O)N)\C)C)O)OC

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