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Form	MW
Gemigliptin hydrochloride This page	525.82
Gemigliptin	489.36

Gemigliptin hydrochloride

Dipeptidyl Peptidase Inhibitor

Gemigliptin hydrochloride is a selective and reversible inhibitor of dipeptidyl peptidase-4 (DPP-4), with an IC50 of 10.3 nM for human recombinant DPP-4. This compound demonstrates significant anti-glycation properties, making it a valuable tool in the study of advanced glycation end products (AGE) and their association with diabetic complications. Gemigliptin hydrochloride is primarily utilized in research focused on the modulation of glucose metabolism and the management of diabetes-related conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1523530-62-2
Applications	Dipeptidyl Peptidase Inhibitor
Formula	C₁₈H₂₀ClF₈N₅O₂
Molecular Weight	525.82
Synonyms	LC15-0444 hydrochloride
SMILES	FC(F)(C1=C2C(CN(CC2)C(C[C@H](N)CN3CC(F)(CCC3=O)F)=O)=NC(C(F)(F)F)=N1)F.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.