Fig. 1 · Structure
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Gemigliptin tartrate hydrate
Dipeptidyl Peptidase Inhibitor
Gemigliptin tartrate hydrate is a selective and reversible inhibitor of dipeptidyl peptidase-4 (DPP-4), exhibiting an IC50 of 10.3 nM against human recombinant DPP-4. This compound demonstrates significant anti-glycation activity and is a valuable tool for investigating advanced glycation end products (AGEs) in the context of diabetic complications. Its application in research can help elucidate the mechanisms underlying AGE-related pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1375415-82-9 |
| Applications | Dipeptidyl Peptidase Inhibitor |
| Formula | C18H19F8N5O2.C4H6O6.3/2H2O |
| Molecular Weight | 666.49 |
| Synonyms | LC15-0444 tartrate hydrate |
| SMILES | OC([C@H](O)[C@@H](O)C(O)=O)=O.O=C1N(C[C@@H](N)CC(N2CCC3=C(C(F)(F)F)N=C(C(F)(F)F)N=C3C2)=O)CC(F)(F)CC1.O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.