Catalog No.: A21536

glucosylceramide synthase inhibitor


Genz-123346 Chemical Structure

CAS NO. 943344-58-9

Genz-123346 is a potent, orally available glucosylceramide synthase inhibitor.

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Biological Activity

Genz-123346 is a potent, orally available glucosylceramide synthase inhibitor.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.13 mL 50.65 mL 101.29 mL
0.5 mM 2.03 mL 10.13 mL 20.26 mL
1 mM 1.01 mL 5.06 mL 10.13 mL
5 mM 0.2 mL 1.01 mL 2.03 mL

*The above data is based on the productmolecular weight 987.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21536
Actions Inhibitor
CAS No. 943344-58-9
Formula C52H82N4O14
M. Wt 987.23
Purity >98%
SMILES CCCCCCCCC(N[[email protected]](CN1CCCC1)[[email protected]@H](C2=CC=C(OCCO3)C3=C2)O)=O.CCCCCCCCC(N[[email protected]](CN4CCCC4)[[email protected]@H](C5=CC=C(OCCO6)C6=C5)O)=O.O=C(O)[[email protected]](O)[[email protected]@H](O)C(O)=O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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