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GFH018 methylbenzenesulfonate

Name: GFH018 methylbenzenesulfonate
Brand: Adooq Bioscience
SKU: A84884
Availability: OutOfStock

Cat. No. A84884 CAS 2345717-52-2

TGF-βRI Inhibitor

GFH018 methylbenzenesulfonate is a selective inhibitor of TGF-β receptor I (TGF-βRI), a key regulator in the TGF-β signaling pathway. By inhibiting TGF-βRI, GFH018 effectively modulates cellular processes related to cancer progression and fibrosis. This reagent is particularly valuable for research applications focused on tumor microenvironment interactions, epithelial-mesenchymal transition, and therapeutic interventions in oncological studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2345717-52-2
Applications	TGF-βRI Inhibitor
Formula	C₂₈H₂₇N₇O₄S
Molecular Weight	557.62
SMILES	NC(/C=C/C1=C(C=CC2=NC=NN21)C3=C(CCC4)N4N=C3C5=CC=CC(C)=N5)=O.O=S(O)(C6=CC=C(C=C6)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.