Fig. 1 · Structure
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GHP-88309
Antiviral Agent
GHP-88309 is a broad-spectrum antiviral agent that inhibits viral polymerase activity, effectively disrupting RNA synthesis in paramyxoviruses. It demonstrates significant antiviral activity against respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV), with an EC50 range of 0.06-1.2 μM. In vivo studies in mouse models further confirm the compound's potent anti-infectious efficacy, making it a valuable tool for research in antiviral therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1269267-87-9 |
| Applications | Antiviral Agent |
| Formula | C16H11FN2O |
| Molecular Weight | 266.27 |
| SMILES | O=C(C1=C(C=CC=C1C2=CC=CC3=C2C=CN=C3)F)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.