Gimeracil-13C3,15N is a stable isotope-labeled analog of Gimeracil, incorporating three carbon-13 and one nitrogen-15 isotopes. Gimeracil, a key component of the oral fluoropyrimidine derivative S-1, functions as a potent inhibitor of dihydropyrimidine dehydrogenase (DPD), thereby inhibiting DNA double-strand break (DSB) repair. This reagent is essential for advanced metabolic studies and pharmacokinetic research involving fluoropyrimidine therapies.
Gimeracil-13C3,15N is a stable isotope-labeled analog of Gimeracil, incorporating three carbon-13 and one nitrogen-15 isotopes. Gimeracil, a key component of the oral fluoropyrimidine derivative S-1, functions as a potent inhibitor of dihydropyrimidine dehydrogenase (DPD), thereby inhibiting DNA double-strand break (DSB) repair. This reagent is essential for advanced metabolic studies and pharmacokinetic research involving fluoropyrimidine therapies.
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