Phenacetin-13C is a stable isotope-labeled derivative of Phenacetin, a non-opioid analgesic and antipyretic agent that selectively inhibits COX-3 enzymes. This compound serves as a valuable tool in pharmacokinetic studies and metabolic profiling, particularly as a probe for cytochrome P450 enzymes CYP1A2 in human liver microsomes and rat models. Its utility in assessing drug metabolism and disposition makes it a critical reagent for researchers investigating analgesic mechanisms and metabolic pathways.
Phenacetin-13C is a stable isotope-labeled derivative of Phenacetin, a non-opioid analgesic and antipyretic agent that selectively inhibits COX-3 enzymes. This compound serves as a valuable tool in pharmacokinetic studies and metabolic profiling, particularly as a probe for cytochrome P450 enzymes CYP1A2 in human liver microsomes and rat models. Its utility in assessing drug metabolism and disposition makes it a critical reagent for researchers investigating analgesic mechanisms and metabolic pathways.
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