Gln144-PLP (139-151)

Catalog No.: A65698
Antigen Peptide Segment
[Gln144]-PLP (139-151) is an experimental antigen peptide segment designed to engage T-cell receptors (TCR) and activate T cells. This activation plays a crucial role in examining the immune response to both autoantigens and cross-reactive non-autoantigens. Its applications extend to the investigation of the underlying mechanisms involved in the regulation of autoimmune diseases, providing insights into potential therapeutic approaches.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description[Gln144]-PLP (139-151) is an experimental antigen peptide segment designed to engage T-cell receptors (TCR) and activate T cells. This activation plays a crucial role in examining the immune response to both autoantigens and cross-reactive non-autoantigens. Its applications extend to the investigation of the underlying mechanisms involved in the regulation of autoimmune diseases, providing insights into potential therapeutic approaches.
Product Information
Catalog NumA65698
FormulaC66H102N20O18
Molecular Weight1463.64
CAS Number170033-42-8
SequenceHis-Ser-Leu-Gly-Lys-Gln-Leu-Gly-His-Pro-Asp-Lys-Phe
Sequence shorteningHSLGKQLGHPDKF
SMILESC([C@H](CC1=CN=CN1)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)N)=O)CO)=O)CC(C)C)=O)=O)CCCCN)=O)CCC(N)=O)=O)CC(C)C)=O)=O)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)CCCCN)=O)CC(O)=O)=O)CCC3
SynonymsQ144-PLP(139-151)
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