Glp5,(Me)Phe8,Sar9 Substance P (5-11)

Catalog No.: A62000
Substance P Analogue
[Glp5,(Me)Phe8,Sar9] Substance P (5-11) is a Substance P analogue that selectively activates the neurokinin 1 receptor (NK1R) in the rat brain, exhibiting effects similar to those of Substance P with an extended duration of action. This compound plays a significant role in modulating dopamine metabolism within the mesencephalon and midbrain cortex. Additionally, [Glp5,(Me)Phe8,Sar9] Substance P (5-11) has been shown to enhance motor activity and facilitate recovery from addictive behavior in rodent models, making it a valuable tool in neuropharmacological research.
Grouped product items
Size Price Stock Qty
1mg
$25.00
In stock
5mg
$55.00
In stock
10mg
$90.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description[Glp5,(Me)Phe8,Sar9] Substance P (5-11) is a Substance P analogue that selectively activates the neurokinin 1 receptor (NK1R) in the rat brain, exhibiting effects similar to those of Substance P with an extended duration of action. This compound plays a significant role in modulating dopamine metabolism within the mesencephalon and midbrain cortex. Additionally, [Glp5,(Me)Phe8,Sar9] Substance P (5-11) has been shown to enhance motor activity and facilitate recovery from addictive behavior in rodent models, making it a valuable tool in neuropharmacological research.
Product Information
Catalog NumA62000
FormulaC43H61N9O9S
Molecular Weight880.06
CAS Number77128-69-9
SequencepGlu-Gln-Phe-N-Methyl-Phe-Sar-Leu-Met-NH2
Sequence shorteningpGlp-QF(-Me)F-Sar-LM-NH2
SMILESCSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CN(C)C(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCC(=O)N1)C(N)=O
SynonymsDiMe-C7
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