[Glp5,(Me)Phe8,Sar9] Substance P (5-11) is a Substance P analogue that selectively activates the neurokinin 1 receptor (NK1R) in the rat brain, exhibiting effects similar to those of Substance P with an extended duration of action. This compound plays a significant role in modulating dopamine metabolism within the mesencephalon and midbrain cortex. Additionally, [Glp5,(Me)Phe8,Sar9] Substance P (5-11) has been shown to enhance motor activity and facilitate recovery from addictive behavior in rodent models, making it a valuable tool in neuropharmacological research.
[Glp5,(Me)Phe8,Sar9] Substance P (5-11) is a Substance P analogue that selectively activates the neurokinin 1 receptor (NK1R) in the rat brain, exhibiting effects similar to those of Substance P with an extended duration of action. This compound plays a significant role in modulating dopamine metabolism within the mesencephalon and midbrain cortex. Additionally, [Glp5,(Me)Phe8,Sar9] Substance P (5-11) has been shown to enhance motor activity and facilitate recovery from addictive behavior in rodent models, making it a valuable tool in neuropharmacological research.
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