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GLS1 Inhibitor-6

GLS1 Inhibitor

GLS1 Inhibitor-6 is a selective inhibitor of glutaminase 1 (GLS1), exhibiting an IC50 of 68 nM and demonstrating 220-fold selectivity over GLS2. This compound exhibits significant anti-tumor activity, effectively inhibiting cell proliferation and inducing apoptosis in cancer cells. GLS1 Inhibitor-6 is a valuable tool for research in cancer metabolism and therapeutic strategies targeting glutamine dependency in tumor growth.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3033615-55-0
Applications	GLS1 Inhibitor
Formula	C₃₇H₅₂N₆O₃S
Molecular Weight	660.91
SMILES	O=C(NCC1CCN(CCCCCC)CC1)C2=CC=CC(COCCC3CCN(C4=NN=C(NC(CC5=CC=CC=C5)=O)S4)CC3)=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.